3M Lab Scale Harvest and Clarification EMP201RCC020R

Designed to effectively clarify Chinese Hamster Ovary (CHO) cell culture centrates produced by conventional and single-use conical plate (e.g., disc stack) centrifuges, 3M™ Harvest RC Centrate Chromatographic Clarifier is a single-stage chromatography solution that employs a synthetic fibrous anion exchange (AEX) Q-functional chromatography media to enable product recoveries of >95% and cell shear-related impurity reduction.

• Single-stage centrate clarification for process compression and streamlining of process development.
• Enables de-risking of clarification process development, scale-up and tech transfer for faster speed to market.
• Synthetic, functionalized fibrous media provides effective soluble impurity removal in centrate, including DNA and cell shear-related submicron particle reduction.
• Predictable performance scalability for consistent centrate clarification at various process scales.
• The single-mode electrostatic separation mechanism and high-throughput media enable product recoveries of >95%.